NFL Leading 7 Pro Bowl Players, Coach of the Year, Defensive Player of the Year
The Rams played their first game in the Los Angeles area since 1994, a 22-year absence, with a preseason opener against the Dallas Cowboys at the Los Angeles Memorial Coliseum on August 13. The Rams defeated the Cowboys 28–24 in front of a crowd of 89,140, a record attendance for a pre-season game.
On September 12, 2016, the Rams played their first regular season game since returning to Los Angeles, where they lost to the San Francisco 49ers 28–0 at Levi's Stadium. On September 18, in front of over 91,000 fans at the Los Angeles Memorial Coliseum, the Rams beat the Seattle Seahawks 9–3 in their first home regular season game in Los Angeles since 1994, and their first game at the Coliseum since 1979.
On December 12, 2016, the team fired head coach Jeff Fisher after starting the season 4−9. The team announced later that day that John Fassel would be taking over as interim head coach.